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Harry Demopoulos
Harry B. Demopoulos is a researcher in the medical aspects of free radicals, especially in the areas of ischaemic injury, the toxicity of anticancer drugs, and in spinal cord injury. He has also been a film actor and is currently a member of the Board of Trustees of the Doris Duke Charitable Foundation.
==Free radical research==
Ischaemic injury (injury to cells due to oxygen deprivation) is an important cause of morbidity and mortality in humans. For example, most deaths in stroke and heart attack are secondary to ischaemic injury, a consequence of the ischemic cascade. Thus, much research has been done into the causes and treatment of ischaemic injury. One are of this research involves the essential role of free radicals (reactive oxygen species and the like) as modulators of ischaemic injury. This has resulted in therapeutic advances, such as the radical-scavenging neuroprotective agent NXY-059, which was under development for the treatment of stroke.
Demopoulos and his coworkers were active in this research. The opening sentence of a paper by Nita ''et al''. states: "The concept of generation of free radicals during ischemia was first presented by Demopoulos, Flamm and co-workers..."
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